Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

Background Accumulating evidence points to an association between gut microbial
abnormalities and depression disorder. The microbiota-gut-brain axis is an emerging target …

Abstract Meta-analyses, published in 2008–2010, have confirmed abnormally low serum
brain-derived neurotrophic factor (BDNF) concentrations in depressed patients and …

Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …

Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …

Depression is a well-known disabling mental illness characterized by sadness, loss of
interest in activities, and decreased energy. The symptoms of depression are usually …

The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover,
recent studies show that brain-derived neurotrophic factor (BDNF), a member of the …

Abstract Brain-Derived Neurotrophic Factor (BDNF) has attracted increasing interest as
potential biomarker to support the diagnosis or monitor the efficacy of therapies in brain …

Cognitive impairment has been observed in patients with various psychiatric disorders,
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …