Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go

K Wang, C Wang, H Jiang, Y Zhang, W Lin… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide and is increasing in incidence. Local ablative therapy plays a leading role in HCC …

Peptide hydrogels as immunomaterials and their use in cancer immunotherapy delivery

N Falcone, M Ermis, DG Tamay… - Advanced …, 2023 - Wiley Online Library
Peptide‐based hydrogel biomaterials have emerged as an excellent strategy for immune
system modulation. Peptide‐based hydrogels are supramolecular materials that self …

Improving the efficacy of peptide vaccines in cancer immunotherapy

F Zahedipour, K Jamialahmadi, P Zamani… - International …, 2023 - Elsevier
Peptide vaccines have shown great potential in cancer immunotherapy by targeting tumor
antigens and activating the patient's immune system to mount a specific response against …

The nuclear export protein XPO1 provides a peptide ligand for natural killer cells

MD Blunt, H Fisher, RB Schittenhelm, B Mbiribindi… - Science …, 2024 - science.org
XPO1 (Exportin-1/CRM1) is a nuclear export protein that is frequently overexpressed in
cancer and functions as a driver of oncogenesis. Currently small molecules that target XPO1 …

[HTML][HTML] KIR2DS2 expression identifies NK cells with enhanced anticancer activity

MD Blunt, A Vallejo Pulido, JG Fisher… - The Journal of …, 2022 - journals.aai.org
NK cells are promising cellular therapeutics against hematological and solid malignancies.
Immunogenetic studies have identified that various activating killer cell Ig-like receptors …

Relevance of polymorphic KIR and HLA class I genes in NK-cell-based immunotherapies for adult leukemic patients

L Dubreuil, P Chevallier, C Retière, K Gagne - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapies are promising approaches to curing different acute
leukemias. Natural killer (NK) cells are lymphocytes that are efficient in the elimination of …

Natural killer cells and type 1 innate lymphoid cells in hepatocellular carcinoma: Current knowledge and future perspectives

N Jacquelot, C Seillet… - International Journal of …, 2021 - mdpi.com
Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1) are specific innate lymphoid
cell subsets that are key for the detection and elimination of pathogens and cancer cells. In …

Peanut oral immunotherapy: current trends in clinical trials

S Reinwald, JM Rolland, RE O'Hehir… - Immunotherapy …, 2022 - academic.oup.com
Immunotherapy for allergy has been practiced for over 100 years. Low-dose repeated
exposure to specific allergen extracts over several months to years can successfully induce …

[HTML][HTML] Skin as the target for allergy prevention and treatment

A Marques-Mejias, I Bartha, CE Ciaccio… - Annals of Allergy …, 2024 - Elsevier
The fact that genetic and environmental factors could trigger disruption of the epithelial
barrier and subsequently initiate a Th2 inflammatory cascade conversely proposes that …

Immunomodulatory Peptides for Tumor Treatment

Y Song, L Lei, X Cai, H Wei… - Advanced Healthcare …, 2024 - Wiley Online Library
Peptides exhibit various biological activities, including biorecognition, cell targeting, and
tumor penetration, and can stimulate immune cells to elicit immune responses for tumor …