[HTML][HTML] Gene therapy: an emerging therapy for hair cells regeneration in the cochlea
J Wang, J Zheng, H Wang, H He, S Li… - Frontiers in …, 2023 - frontiersin.org
Sensorineural hearing loss is typically caused by damage to the cochlear hair cells (HCs)
due to external stimuli or because of one's genetic factors and the inability to convert sound …
due to external stimuli or because of one's genetic factors and the inability to convert sound …
[HTML][HTML] Research progress on flat epithelium of the inner ear
HE Lu, GUO Jing-Ying, LIU Ke, W Guo-Peng… - Physiological …, 2020 - ncbi.nlm.nih.gov
Sensorineural hearing loss and vertigo, resulting from lesions in the sensory epithelium of
the inner ear, have a high incidence worldwide. The sensory epithelium of the inner ear may …
the inner ear, have a high incidence worldwide. The sensory epithelium of the inner ear may …
Regenerative therapy approaches and encountered problems in sensorineural hearing loss
K Kelleci, E Golebetmaz - Current Stem Cell Research & …, 2023 - ingentaconnect.com
Hearing loss is one of the most important public health matters worldwide, severely affecting
people's social, psychological, and cognitive development. The perception of sound …
people's social, psychological, and cognitive development. The perception of sound …
[HTML][HTML] Simultaneous gentamicin-mediated damage and Atoh1 overexpression promotes hair cell regeneration in the neonatal mouse utricle
X Qian, R Ma, X Wang, X Xu, J Yang, F Chi… - Experimental cell …, 2021 - Elsevier
Loss of hair cells from vestibular epithelium results in balance dysfunction. The current
therapeutic regimen for vestibular diseases is limited. Upon injury or Atoh1 overexpression …
therapeutic regimen for vestibular diseases is limited. Upon injury or Atoh1 overexpression …
AAV8-mediated Atoh1 overexpression induces dose-dependent regeneration of vestibular hair cells in adult mice
JY Guo, L He, ZR Chen, K Liu, SS Gong, GP Wang - Neuroscience letters, 2021 - Elsevier
Vestibular hair cells (HCs) are mechanoreceptors for the detection of head movement.
Vestibular HCs of adult mammals never completely regenerate after damage, resulting in …
Vestibular HCs of adult mammals never completely regenerate after damage, resulting in …
Mammalian Hair Cell Regeneration
R Taylor, A Forge - Hair Cell Regeneration, 2023 - Springer
In adult mammals, there is no hair cell regeneration in the cochlea and a limited capacity in
the vestibular organs. Research in this area is directed toward uncovering a latent potential …
the vestibular organs. Research in this area is directed toward uncovering a latent potential …
[图书][B] Determining the Role of Gata3 in a Sub-population of Vestibular Hair Cells
S Sheltz-Kempf - 2022 - search.proquest.com
The inner ear can be divided based on two functions: hearing and balance. The hearing
organ is called the cochlea, while the organs responsible for balance are collectively called …
organ is called the cochlea, while the organs responsible for balance are collectively called …
[HTML][HTML] AAV-ie-mediated UCP2 overexpression accelerates inner hair cell loss during aging in vivo
C Zhao, Z Yang, Z Chen, W Liang, S Gong, Z Du - Molecular Medicine, 2022 - Springer
Abstract Background Uncoupling protein 2 (UCP2), activated by excessive reactive oxygen
species (ROS) in vivo, has the dual effect of reducing ROS to protect against oxidative stress …
species (ROS) in vivo, has the dual effect of reducing ROS to protect against oxidative stress …