This review is aimed to provide extensive survey of quinolones and fluoroquinolones for a
variety of applications ranging from metal complexes and nanoparticle development to …

The properties of pyrimidine and pyrazine derivatives responsible for the existence of
antituberculosis activity are considered. Examples of synthesis and biological activity of the …

Tuberculosis remains as a major public health risk which causes the highest mortality rate
globally and an improved regimen is required to treat the drug-resistant strains …

Novel fluoroquinolone–pyrazine conjugates 7a–h with amino acid linkers were synthesized
in good yields utilizing benzotriazole chemistry. Antimicrobial bioassay showed that the …

A series of twenty new chloropyrazine conjugated benzothiazepines (22–41) have been
synthesized with 58%–95% yields. The compounds were characterized by using different …

The molecular structural parameters and vibrational frequencies of 5-chloro-N-(3-
nitrophenyl) pyrazine-2-carboxamide have been obtained using density functional theory …

The optimized molecular structure, vibrational frequencies, corresponding vibrational
assignments of 2-(4-methoxyphenyl)-4, 5-dimethyl-1H-imidazole 3-oxide have been …

In this study, a series of twenty-two ring-substituted 6-hydroxynaphthalene-2-carboxanilides
was prepared and characterized. Primary in vitro screening of the synthesized compounds …

Aminodehalogenation of 3-chloropyrazine-2-carboxamide with variously substituted
benzylamines yielded a series of fifteen 3-benzylaminopyrazine-2-carboxamides. Four …

5-Chloropyrazinamide (5-Cl-PZA) is an inhibitor of mycobacterial fatty acid synthase I with a
broad spectrum of antimycobacterial activity in vitro. Some N-phenylpyrazine-2 …