Mechanisms of ATP release and signalling in the blood vessel wall
Abstract The nucleotide adenosine 5′-triphosphate (ATP) has classically been considered
the cell's primary energy currency. Importantly, a novel role for ATP as an extracellular …
the cell's primary energy currency. Importantly, a novel role for ATP as an extracellular …
Extracellular nucleosides and nucleotides as immunomodulators
Some anticancer agents induce immunogenic cell death that is accompanied by the
emission of danger signals into the tumor microenvironment, thus attracting and activating …
emission of danger signals into the tumor microenvironment, thus attracting and activating …
Stimulation-dependent release of adenosine triphosphate from hippocampal slices
A Wieraszko, G Goldsmith, TN Seyfried - Brain research, 1989 - Elsevier
Schaffer collaterals of rat and mouse hippocampal slices were stimulated with bursts of
pulses (300 Hz for 50 ms, 2-s intervals) for 30-s which caused a stable increase in the size of …
pulses (300 Hz for 50 ms, 2-s intervals) for 30-s which caused a stable increase in the size of …
Noradrenaline and ATP as cotransmitters in sympathetic nerves
G Burnstock - Neurochemistry international, 1990 - Elsevier
Evidence is presented in support of the view that adenosine 5′-triphosphate (ATP) is a
cotransmitter with noradrenaline (NA) in sympathetic nerves supplying the vas deferens and …
cotransmitter with noradrenaline (NA) in sympathetic nerves supplying the vas deferens and …
Expression of pannexin isoforms in the systemic murine arterial network
Aims: Pannexins (Panx) form ATP release channels and it has been proposed that they play
an important role in the regulation of vascular tone. However, distribution of Panx across the …
an important role in the regulation of vascular tone. However, distribution of Panx across the …
The purinergic neurotransmitter revisited: a single substance or multiple players?
VN Mutafova-Yambolieva, L Durnin - Pharmacology & Therapeutics, 2014 - Elsevier
The past half century has witnessed tremendous advances in our understanding of
extracellular purinergic signaling pathways. Purinergic neurotransmission, in particular, has …
extracellular purinergic signaling pathways. Purinergic neurotransmission, in particular, has …
Purinergic signalling in the reproductive system in health and disease
G Burnstock - Purinergic signalling, 2014 - Springer
There are multiple roles for purinergic signalling in both male and female reproductive
organs. ATP, released as a cotransmitter with noradrenaline from sympathetic nerves …
organs. ATP, released as a cotransmitter with noradrenaline from sympathetic nerves …
Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-κB ligand
KA Buckley, RA Hipskind, A Gartland, WB Bowler… - Bone, 2002 - Elsevier
Nucleotides such as adenosine triphosphate (ATP) and uridine triphosphate (UTP) exist in
the extracellular environment where they are agonists at P2 receptors. Both P2Y G-protein …
the extracellular environment where they are agonists at P2 receptors. Both P2Y G-protein …
Purinergic dysregulation in pulmonary hypertension
SH Visovatti, MC Hyman… - American Journal …, 2016 - journals.physiology.org
Despite the fact that nucleotides and adenosine help regulate vascular tone through
purinergic signaling pathways, little is known regarding their contributions to the …
purinergic signaling pathways, little is known regarding their contributions to the …
Release and interconversion of P2 receptor agonists by human osteoblast‐like cells
KA Buckley, SL Golding, JM Rice, JP Dillon… - The FASEB …, 2003 - Wiley Online Library
Nucleotides, acting as agonists at P2 receptors, are important extracellular signaling
molecules in many tissues. In bone they affect both bone‐forming osteoblast and bone …
molecules in many tissues. In bone they affect both bone‐forming osteoblast and bone …