Bronchiolitis needs a revisit: distinguishing between virus entities and their treatments

T Jartti, HH Smits, K Bønnelykke, O Bircan, V Elenius… - Allergy, 2019 - Wiley Online Library
Current data indicate that the “bronchiolitis” diagnosis comprises more than one condition.
Clinically, pathophysiologically, and even genetically three main clusters of patients can be …

[HTML][HTML] Role of the microbiota in lung cancer: insights on prevention and treatment

F Pizzo, Z Maroccia, I Hammarberg Ferri… - International Journal of …, 2022 - mdpi.com
The microbiota is increasingly recognized as a critical player in cancer onset and
progression and response to cancer chemotherapy treatment. In recent years, several …

Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma

J Stokholm, J Thorsen, MJ Blaser… - Science translational …, 2020 - science.org
There have been reports of associations between cesarean section delivery and the risk of
childhood asthma, potentially mediated through changes in the gut microbiota. We followed …

[HTML][HTML] The infant gut resistome associates with E. coli, environmental exposures, gut microbiome maturity, and asthma-associated bacterial composition

X Li, J Stokholm, A Brejnrod, GA Vestergaard… - Cell host & …, 2021 - cell.com
Antimicrobial resistance (AMR) is an accelerating global threat, yet the nature of AMR in the
gut microbiome and how AMR is acquired during early life remain largely unknown. In a …

[HTML][HTML] Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

J Thorsen, MA Rasmussen, J Waage… - Nature …, 2019 - nature.com
Asthma is believed to arise through early life aberrant immune development in response to
environmental exposures that may influence the airway microbiota. Here, we examine the …

[HTML][HTML] Amplicon sequencing provides more accurate microbiome information in healthy children compared to culturing

S Gupta, MS Mortensen, S Schjørring, U Trivedi… - Communications …, 2019 - nature.com
Abstract Next-Generation Sequencing (NGS) of 16S rRNA gene is now one of the most
widely used application to investigate the microbiota at any given body site in research …

Urbanized microbiota in infants, immune constitution, and later risk of atopic diseases

J Lehtimäki, J Thorsen, MA Rasmussen… - Journal of Allergy and …, 2021 - Elsevier
Background Urbanization is linked with an increased burden of asthma and atopic traits. A
putative mechanism is insufficient exposure to beneficial microbes early in life, leading to …

Characterization of lung and oral microbiomes in lung cancer patients using culturomics and 16S rRNA gene sequencing

Y Sun, Y Liu, J Li, Y Tan, T An, M Zhuo… - Microbiology …, 2023 - Am Soc Microbiol
Recently, microbiota dysbiosis in lung cancer has attracted immense attention. Studies on
lung microbes are mostly based on sequencing, which has left the potentially functional …

[HTML][HTML] The developing airway and gut microbiota in early life is influenced by age of older siblings

ED Christensen, MH Hjelmsø, J Thorsen, S Shah… - Microbiome, 2022 - Springer
Background Growing up with siblings has been linked to numerous health outcomes and is
also an important determinant for the developing microbiota. Nonetheless, research into the …

[HTML][HTML] Modeling transfer of vaginal microbiota from mother to infant in early life

MS Mortensen, MA Rasmussen, J Stokholm… - Elife, 2021 - elifesciences.org
Early-life microbiota has been linked to the development of chronic inflammatory diseases. It
has been hypothesized that maternal vaginal microbiota is an important initial seeding …