In this review, subtypes of functional α1-and α2-adrenoceptors are discussed. These are cell
membrane receptors, belonging to the seven transmembrane spanning G-protein-linked …

The concept of pre-and postjunctionally located a adrenoceptors, as well as the more recent
subdivision into ax and a2 subtypes, has initiated duringthe last decade a renaissance of …

1 The activity on α‐adrenoreceptors of medetomidine (±)‐4‐(α, 2, 3‐trimethylbenzyl)
imidazole), an α‐methyl derivative of detomidine, has been characterized in vivo and in vitro …

In this review the classification of a-adrenoceptors into two major subgroups is discussed, an
idea which derived primarily from studies on the pre-and postsynaptic a-receptors at …

The concept of two types of alpha-adrenoceptor, alpha 1 located on smooth muscle and
mediating contraction and alpha 2 located on nerve terminals and mediating inhibition of …

Abstract α-Adrenoceptors may be subdivided based on their anatomical distribution within
the synapse. Presynaptic α-adrenoceptors are generally of the α 2-subtype and modulate …

Alpha-adrenoceptors are present on the varicosity membrane of noradrenergic nerve
endings where they participate in modulation of noradrenaline release. Activation of these …

ABSTRACT van Meel, JCA, A. de Jonge, PBMWM Timmermans and PA van Zwieten:
Selectivity of some alpha adrenoceptor agonists for peripheral alpha-i and alpha-2 …

The hemodynamic effects of clonidine were studied in four patients with severe idiopathic
Orthostatic hypotension and one patient with baroreceptor dysfunction. No depressor …

Alpha-adrenergic receptors play an important role in the regulation of blood pressure (BP).
There are 2 principal types of α receptors, α 1 and α 2, and both participate in circulatory …