Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Alveolar lipids in pulmonary disease. A review
CW Agudelo, G Samaha, I Garcia-Arcos - Lipids in health and disease, 2020 - Springer
Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is
composed by multiple cell types with specialized functions and coordinately acting to meet …
composed by multiple cell types with specialized functions and coordinately acting to meet …
The clinical use of corticosteroids in pregnancy
BACKGROUND The use of antenatal steroid therapy is common in pregnancy. In early
pregnancy, steroids may be used in women for the treatment of recurrent miscarriage or fetal …
pregnancy, steroids may be used in women for the treatment of recurrent miscarriage or fetal …
[HTML][HTML] Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy
E Lopez-Rodriguez, J Pérez-Gil - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Pulmonary surfactant is an essential lipid–protein complex to maintain an operative
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
[HTML][HTML] Dysregulation of metabolic pathways in pulmonary fibrosis
R Rajesh, R Atallah, T Bärnthaler - Pharmacology & Therapeutics, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …
Lipid–protein and protein–protein interactions in the pulmonary surfactant system and their role in lung homeostasis
O Cañadas, B Olmeda, A Alonso… - International journal of …, 2020 - mdpi.com
Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …
[HTML][HTML] Restoring pulmonary surfactant membranes and films at the respiratory surface
Pulmonary surfactant is a complex of lipids and proteins assembled and secreted by the
alveolar epithelium into the thin layer of fluid coating the respiratory surface of lungs. There …
alveolar epithelium into the thin layer of fluid coating the respiratory surface of lungs. There …
Atomic force microscopy to study molecular mechanisms of amyloid fibril formation and toxicity in Alzheimer's disease
Alzheimer's disease (AD) is a devastating neurodegenerative disease characterized by
dementia and memory loss for which no cure or effective prevention is currently available …
dementia and memory loss for which no cure or effective prevention is currently available …
Combined and independent action of proteins SP-B and SP-C in the surface behavior and mechanical stability of pulmonary surfactant films
The hydrophobic proteins SP-B and SP-C are essential for pulmonary surfactant function,
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …