Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease
During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …
many populations. While uric acid is usually discussed in the context of gout …
The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors
N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
Uric acid and cardiovascular disease
G Ndrepepa - Clinica chimica acta, 2018 - Elsevier
Uric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as
an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in …
an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in …
[HTML][HTML] Physiology of hyperuricemia and urate-lowering treatments
CL Benn, P Dua, R Gurrell, P Loudon, A Pike… - Frontiers in …, 2018 - frontiersin.org
Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …
typically characterized by hyperuricemia and monosodium urate crystal deposition …
Uric acid and hypertension: a review of evidence and future perspectives for the management of cardiovascular risk
Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …
directly involved in the pathogenesis and natural history of hypertension. The relationship …
Hyperuricemia and risk of cardiovascular outcomes: the experience of the URRAH (uric acid right for heart health) project
A Maloberti, C Giannattasio, M Bombelli… - High Blood Pressure & …, 2020 - Springer
Abstract The latest European Guidelines of Arterial Hypertension have officially introduced
uric acid evaluation among the cardiovascular risk factors that should be evaluated in order …
uric acid evaluation among the cardiovascular risk factors that should be evaluated in order …
[HTML][HTML] Hyperuricemia-related diseases and xanthine oxidoreductase (XOR) inhibitors: an overview
C Chen, JM Lü, Q Yao - Medical science monitor: international …, 2016 - ncbi.nlm.nih.gov
Uric acid is the final oxidation product of purine metabolism in humans. Xanthine
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …
A Hydrogel Microneedle Assay Combined with Nucleic Acid Probes for On‐Site Detection of Small Molecules and Proteins
Point‐of‐care testing (POCT) of clinical biomarkers is critical to health monitoring and timely
treatment, yet biosensing assays capable of detecting biomarkers without the need for costly …
treatment, yet biosensing assays capable of detecting biomarkers without the need for costly …
Hyperuricemia and cardiovascular disease
S Zhang, Y Wang, J Cheng, N Huangfu… - Current …, 2019 - ingentaconnect.com
Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …
[HTML][HTML] Management of hyperuricemia in patients with chronic kidney disease: a focus on renal protection
JT Kielstein, R Pontremoli, M Burnier - Current Hypertension Reports, 2020 - Springer
Abstract Purpose of Review In chronic kidney disease (CKD), plasma uric acid levels are
increased because of the decrease in glomerular filtration rate. However, in addition to CKD …
increased because of the decrease in glomerular filtration rate. However, in addition to CKD …