Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Arterial stiffening, at least, reflects gradual fragmentation and loss of elastin fibers and
accumulation of stiffer collagen fibers in the media of large arteries and occurs …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Ageing is associated with functional, structural and mechanical changes in arteries that
closely resemble the vascular alterations in hypertension. Characteristic features of large …

Background: Primary aldosteronism is recognized as a severe form of renin-independent
aldosteronism that results in excessive mineralocorticoid receptor (MR) activation. Objective …

Primary aldosteronism is a severe form of autonomous aldosteronism. Milder forms of
autonomous and renin-independent aldosteronism may be common, even in normotension …

Background: Both aging and inappropriate secretion of aldosterone increase the risk for
developing cardiovascular disease; however, the influence of aging on aldosterone …

Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …