Bacterial chromosomes are folded to compact DNA and facilitate cellular processes.
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …

Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

Emerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs)
and transcription contribute in combination to the dynamic nature of nucleoid structure …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …

Background Helicobacter pylori is well adapted to colonize the epithelial surface of the
human gastric mucosa and can cause persistent infections. In order to infect the gastric …

Bacterial nucleoid-associated proteins play a key role in the organisation, replication,
segregation, repair and expression of bacterial chromosomes. Here, we review some recent …

Research into post‐transcriptional control of mRNAs by small noncoding RNAs (sRNAs) in
the model bacteria Escherichia coli and Salmonella enterica has mainly focused on sRNAs …

Bacteria that cause chronic and/or recurrent diseases often rely on a biofilm lifestyle. The
foundation of the biofilm structure is the extracellular polymeric substance (EPS) that acts as …

Genome architecture has proven to be critical in determining gene regulation across almost
all domains of life. While many of the key components and mechanisms of eukaryotic …