Quinoline hydrazide/hydrazone derivatives: Recent insights on antibacterial activity and mechanism of action
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
Recent developments in the synthesis of hybrid antimalarial drug discovery
In this 21 st century, Malaria remains a global burden and causes massive economic trouble
to disease-endemic nations. The control and eradication of malaria is a major challenge that …
to disease-endemic nations. The control and eradication of malaria is a major challenge that …
Quinoline: a promising scaffold in recent antiprotozoal drug discovery
A Dorababu - ChemistrySelect, 2021 - Wiley Online Library
Protozoal infections malaria and leishmania have become most prevalent in recent times. A
high death rate is reported world‐wide because of these diseases. Although there are only a …
high death rate is reported world‐wide because of these diseases. Although there are only a …
Recent contributions of quinolines to antimalarial and anticancer drug discovery research
T Van de Walle, L Cools, S Mangelinckx… - European Journal of …, 2021 - Elsevier
Quinoline, a privileged scaffold in medicinal chemistry, has always been associated with a
multitude of biological activities. Especially in antimalarial and anticancer research …
multitude of biological activities. Especially in antimalarial and anticancer research …
Synthesis of novel quinoline‐thiosemicarbazide hybrids and evaluation of their biological activities, molecular docking, molecular dynamics, pharmacophore model …
In the present study, a novel series of N‐((substituted) carbamothioyl)‐2, 4‐
dimethylquinoline‐3‐carboxamide (7a‐7s) was synthesized by microwave‐assisted method …
dimethylquinoline‐3‐carboxamide (7a‐7s) was synthesized by microwave‐assisted method …
Design, Synthesis, and Biological and In Silico Study of Fluorine‐Containing Quinoline Hybrid Thiosemicarbazide Analogues
A novel series of fluorine‐containing quinoline hybrid thiosemicarbazide analogues (8a–8l)
were synthesized and tested for their biological activities. The antibacterial results …
were synthesized and tested for their biological activities. The antibacterial results …
Synthesis, docking study and biological evaluation of novel N-(1, 3-benzothiazole-2-yl)-2-(pyridine-3-ylformohydrazido) acetamide derivatives
A series of N-(1, 3-benzothiazole-2-yl)-2 (pyridine-3-ylformohydrazido acetamide derivatives
have been synthesized by facile and efficient conventional method. The structures of the …
have been synthesized by facile and efficient conventional method. The structures of the …