Novel Cancer Prevention Strategies in Individuals With Hereditary Cancer Syndromes: Focus on BRCA1, BRCA2, and Lynch Syndrome

CM Bowen, K Demarest, E Vilar… - American Society of …, 2024 - ascopubs.org
Germline pathogenic variants (PVs) in the BRCA1 and BRCA2 genes confer elevated risks
of breast, ovarian, and other cancers. Lynch syndrome (LS) is associated with increased …

Immunoprevention Strategies for Colorectal Cancer in Lynch Syndrome Carriers

CM Bowen, KM Sinha, E Vilar - The Cancer Journal, 2024 - journals.lww.com
The immune revolution that swept the field of oncology in the mid-2010s with the advent of
checkpoint inhibitors has led to a paradigm shift in approaches toward adapting new cancer …