The past decades witnessed an increasing interest in peptides as clinical therapeutics.
Rightfully considered as a potential alternative for small molecule therapy, these remarkable …

Peptide-based drugs are gaining significant momentum in the modern drug discovery, which
is witnessed by the approval of new drugs by the FDA in recent years. On the other hand …

The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

Peptides have gained more and more interest as therapeutics for different fields of medical
indications. Built up via a peptide bond from naturally occurring amino acids they stand out …

Cell-penetrating peptides represent an emerging class of carriers capable of effective
cellular delivery. This work demonstrates the preparation and investigation of efficient CPPs …

Cell-penetrating peptides (CPPs) are promising delivery vehicles. These short peptides can
transport wide range of cargos into cells, although their usage has often limitations. One of …

The cell-penetrating peptide (CPP) penetratin has gained much attention over many years
due to its potential role as a transporter for a broad range of cargo into cells. The …

Delivering therapeutic agents into cells has always been a major challenge. In recent years,
cyclization emerged as a tool for designing CPPs to increase their internalization and …

Cell-penetrating peptides (CPPs) are commonly modified to increase their cellular uptake,
alter the mechanism of penetration or enhance their endosomal release. Earlier, we …

Vinca alkaloids are well‐known microtubule targeting agents, which are used against some
types of cancer. Vindoline is one of the monomeric Vinca alkaloids which does not have anti …