The term vascular cognitive impairment (VCI) was introduced around the start of the new
millennium and refers to the contribution of vascular pathology to any severity of cognitive …

The notion of what qualifies as vascular dementia has varied greatly since the first mention
of dementia after apoplexy in ancient literature. Current insight points towards a …

Background Chronic cerebral hypoperfusion (CCH) underlies secondary brain injury
following certain metabolic disorders and central nervous system (CNS) diseases …

Alzheimer's disease (AD) is the most frequent cause of dementia, where the abnormal
accumulation of beta-amyloid (Aβ) and tau lead to neurodegeneration as well as loss of …

On 7 June 2021, aducanumab was granted accelerated approval for the treatment of
Alzheimer disease (AD) by the FDA on the basis of amyloid-lowering effects considered …

Aging is characterized by a morpho-functional adaptation, variably affecting major
physiological systems, depending on a complex interaction between genetic, environmental …

Abstract Both type 1 (T1DM) and type 2 diabetes mellitus (T2DM) have been associated with
reduced performance on multiple domains of cognitive function and with evidence of …

A growing body of evidence suggests that adherence to the Mediterranean diet (MD) may
protect against cognitive decline and dementia. Many epidemiologic studies and several …

The increase in the prevalence of obesity represents a worldwide phenomenon in all age
groups and is pathologically and genetically correlated with several metabolic and …

Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …