Emerging strategies for EphA2 receptor targeting for cancer therapeutics
Importance of the field: High mortality rates with cancers warrant further development of
earlier diagnostics and better treatment strategies. Membrane-bound erythropoietin …
earlier diagnostics and better treatment strategies. Membrane-bound erythropoietin …
Eph receptors and ephrins as targets for cancer therapy
HQ Xi, XS Wu, B Wei, L Chen - Journal of cellular and …, 2012 - Wiley Online Library
Eph receptor tyrosine kinases and their ephrin ligands are involved in various signalling
pathways and mediate critical steps of a wide variety of physiological and pathological …
pathways and mediate critical steps of a wide variety of physiological and pathological …
EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells
J Huang, D Xiao, G Li, J Ma, P Chen, W Yuan, F Hou… - Oncogene, 2014 - nature.com
This study aims to investigate the significance of erythropoietin-producing hepatocellular
(Eph) A2 expression and the mechanism by which EphA2 is involved in the epithelial …
(Eph) A2 expression and the mechanism by which EphA2 is involved in the epithelial …
Ephrin-A2 promotes prostate cancer metastasis by enhancing angiogenesis and promoting EMT
Y Zhao, C Cai, M Zhang, L Shi, J Wang… - Journal of Cancer …, 2021 - Springer
Background Ephrin-A2, a member of the Eph receptor subgroup, is used in diagnosing and
determining the prognosis of prostate cancer. However, the role of ephrin-A2 in prostate …
determining the prognosis of prostate cancer. However, the role of ephrin-A2 in prostate …
Eph-dependent cell-cell adhesion and segregation in development and cancer
E Nievergall, M Lackmann, PW Janes - Cellular and Molecular Life …, 2012 - Springer
Numerous studies attest to essential roles for Eph receptors and their ephrin ligands in
controlling cell positioning and tissue patterning during normal and oncogenic development …
controlling cell positioning and tissue patterning during normal and oncogenic development …
Immunotherapy against several tumors including gastrointestinal and gastric cancer
J Fritsche, T Weinschenk, S Walter… - US Patent …, 2015 - Google Patents
The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …
immunotherapeutic methods. In particular, the present invention relates to the …
The role of Eph receptors and ephrin ligands in colorectal cancer
NI Herath, AW Boyd - International Journal of Cancer, 2010 - Wiley Online Library
Eph receptors and their ephrin ligands constitute the largest subfamily of receptor tyrosine
kinases and are components of the cell signaling pathways involved during development …
kinases and are components of the cell signaling pathways involved during development …
EphA3 biology and cancer
Eph receptor tyrosine kinases control cell-cell interactions during normal and oncogenic
development, and are implicated in a range of processes including angiogenesis, stem cell …
development, and are implicated in a range of processes including angiogenesis, stem cell …
EPHA2, EPHA4, and EPHA7 expression in triple-negative breast cancer
I Nikas, C Giaginis, K Petrouska, P Alexandrou… - Diagnostics, 2022 - mdpi.com
Ongoing research continues to elucidate the complex role of ephrin receptors (EPHs) and
their ligands (ephrins) in breast cancer pathogenesis, with their varying expression patterns …
their ligands (ephrins) in breast cancer pathogenesis, with their varying expression patterns …
Emerging therapeutic targets for gastric cancer from a host-Helicobacter pylori interaction perspective
E Abdi, S Latifi-Navid, F Abedi Sarvestani… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Gastric cancer (GC) has the higher genetic, cytologic, and architectural
heterogeneity compared to other gastrointestinal cancers. By inducing gastric inflammation …
heterogeneity compared to other gastrointestinal cancers. By inducing gastric inflammation …