Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis of
tumor cells and their spread to various organs and tissues of body, providing undesirable …

Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …

Background Opioid-induced immunomodulation may be of particular importance in triple-
negative breast cancer (TNBC) where an immune response is associated with improved …

Breast cancer with bone metastasis accounts for serious cancer‐associated pain which
significantly reduces the quality of life of affected patients and promotes cancer progression …

The US is grappling with an opioid epidemic, with millions of adults on long-term opioid
therapy (LTOT). Although patients often report pain relief and improved daily function with …

Background Triple-negative breast cancer (TNBC) is relatively common in women and is
associated with a poor prognosis after surgery and adjuvant chemotherapy. Currently, the …

Pain is one of the most burdensome symptoms in people with cancer, and opioid analgesics
are considered the mainstay of cancer pain management. For this review, the authors …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

The integration of EEG monitoring is crucial for guiding adequate multimodal anaesthesia
and preventing excessive anaesthesia dosing. Furthermore, the review investigates the …

The κ‑opioid receptor (KOR) is one of the primary receptors of opioids and serves a vital role
in the regulation of pain, anesthesia, addiction and other pathological and physiological …