Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …

Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of
compounds into cells. Since the discovery of the first members of this peptide family, many …

We developed a pH-activatable cell-penetrating peptide dimer LH 2 with histidine residues,
which can penetrate cells, specifically in weak acidic conditions, even at few tens of …

Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …

According to the World Health Organization, cancer is one of the leading causes of morbidity
and mortality worldwide. The previously estimated 14 million new cases in the year of 2012 …

To conquer the drug resistance of tumors and the poor solubility of paclitaxel (PTX), two PTX-
cell-penetrating peptide conjugates (PTX-CPPs), PTX-TAT and PTX-LMWP, were …

The past decades witnessed an increasing interest in peptides as clinical therapeutics.
Rightfully considered as a potential alternative for small molecule therapy, these remarkable …

Cytotoxic peptides derived from spider venoms have been considered as promising
candidates for anticancer treatment. The novel cell penetrating peptide LVTX-8, which is a …

Cell-penetrating peptides represent an emerging class of carriers capable of effective
cellular delivery. This work demonstrates the preparation and investigation of efficient CPPs …