[HTML][HTML] Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

MD Turner, B Nedjai, T Hurst, DJ Pennington - Biochimica et Biophysica …, 2014 - Elsevier
Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …

Roles of the NLRP3 inflammasome in the pathogenesis of diabetic nephropathy

Y Qiu, L Tang - Pharmacological Research, 2016 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes mellitus, and persistent
inflammation in circulatory and renal tissues is an important pathophysiological basis for DN …

Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet …

Y Zhu, C Zhu, H Yang, J Deng, D Fan - Pharmacological research, 2020 - Elsevier
Diabetic nephropathy (DN) is a common and serious complication of diabetes and causes
kidney failure. Ginsenoside Rg5 (Rg5) is an important monomer in the main …

Novel insights into NOD-like receptors in renal diseases

J Jin, T Zhou, G Ren, L Cai, X Meng - Acta Pharmacologica Sinica, 2022 - nature.com
Nucleotide-binding oligomerization domain-like receptors (NLRs), including NLRAs, NLRBs
(also known as NAIPs), NLRCs, and NLRPs, are a major subfamily of pattern recognition …

Galangin attenuates mast cell-mediated allergic inflammation

HH Kim, Y Bae, SH Kim - Food and chemical toxicology, 2013 - Elsevier
A great number of people are suffering from allergic inflammatory disease such as asthma,
atopic dermatitis, and sinusitis. Therefore discovery of drugs for the treatment of these …

Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS)

T Bachetti, S Chiesa, P Castagnola, D Bani… - Annals of the …, 2013 - ard.bmj.com
Objectives Tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is
caused by TNFRSF1A mutations, known to induce intracellular retention of the TNFα …

Key facts and hot spots on tumor necrosis factor receptor‐associated periodic syndrome

D Rigante, G Lopalco, A Vitale, OM Lucherini… - Clinical …, 2014 - Springer
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS), formerly known as
familial Hibernian fever, is the most common autosomal dominant autoinflammatory disease …

Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases

R Adhikary, S Sultana, B Bishayi - Journal of ethnopharmacology, 2018 - Elsevier
Abstract Ethnopharmacological relevance Clitoria ternatea Linn.(C. ternatea) is a
traditionally used herb in arthritis, and its anti-arthritic activity has been attributed to …

Tumor necrosis factor receptor-associated periodic syndrome as a model linking autophagy and inflammation in protein aggregation diseases

T Bachetti, I Ceccherini - Journal of Molecular Medicine, 2014 - Springer
Autophagy prevents cellular damage by eliminating insoluble aggregates of mutant
misfolded proteins, which accumulate under different pathological conditions …

[HTML][HTML] Successful treatment of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) with tocilizumab: a case report

N Akasbi, MS Soyfoo - European Journal of Rheumatology, 2015 - ncbi.nlm.nih.gov
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal
dominant autoinflammatory disease linked to chromosome 12p13 and, more specifically …