Mammalian AMPK is known to be activated by falling cellular energy status, signaled by
rising AMP/ATP and ADP/ATP ratios. We review recent information about how this occurs …

Microsporidia are obligate intracellular pathogens identified∼ 150 years ago as the cause
of pébrine, an economically important infection in silkworms. There are about 220 genera …

Budding yeasts (subphylum Saccharomycotina) are found in every biome and are as
genetically diverse as plants or animals. To understand budding yeast evolution, we …

Abstract Iron-sulfur (Fe/S) proteins are present in virtually all living organisms and are
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …

Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

Major insights into the phylogenetic distribution, biochemistry, and evolutionary significance
of organelles involved in ATP synthesis (energy metabolism) in eukaryotes that thrive in …

Microsporidia are obligate intracellular pathogens related to Fungi. These organisms have a
unique invasion organelle, the polar tube, which upon appropriate environmental …

Background The availability of multiple, essentially complete genome sequences of
prokaryotes and eukaryotes spurred both the demand and the opportunity for the …

The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of
malaria, and kills more than one million African children annually. Here we report an …

The ancestors of fungi are believed to be simple aquatic forms with flagellated spores,
similar to members of the extant phylum Chytridiomycota (chytrids). Current classifications …