A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …
important role in many physiological processes and joining nitric oxide and carbon …
International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
[HTML][HTML] Evidence for the involvement of the master transcription factor NF-κB in cancer initiation and progression
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the
regulation of a large number of genes that are involved in important physiological …
regulation of a large number of genes that are involved in important physiological …
[HTML][HTML] Trends in H2S-Donors Chemistry and Their Effects in Cardiovascular Diseases
A Corvino, F Frecentese, E Magli, E Perissutti… - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous gasotransmitter recently emerged as an
important regulatory mediator of numerous human cell functions in health and in disease. In …
important regulatory mediator of numerous human cell functions in health and in disease. In …
Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules
In addition to being notorious air pollutants, nitric oxide (NO), carbon monoxide (CO), and
hydrogen sulfide (H 2 S) have also been known as endogenous gaseous signaling …
hydrogen sulfide (H 2 S) have also been known as endogenous gaseous signaling …
On-demand therapeutic delivery of hydrogen sulfide aided by biomolecules
Y Ge, F Rong, W Li, Y Wang - Journal of Controlled Release, 2022 - Elsevier
Abstract Hydrogen sulfide (H 2 S), known as the third gasotransmitter, exerts various
physiological functions including cardiac protection, angiogenesis, anti-inflammatory, and …
physiological functions including cardiac protection, angiogenesis, anti-inflammatory, and …
[HTML][HTML] Role of hydrogen sulfide donors in cancer development and progression
In recent years, a vast number of potential cancer therapeutic targets have emerged.
However, developing efficient and effective drugs for the targets is of major concern …
However, developing efficient and effective drugs for the targets is of major concern …
Hydrogen sulfide-releasing therapeutics: translation to the clinic
JL Wallace, D Vaughan, M Dicay… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Shortly after the discovery of the role of hydrogen sulfide (H2S) in many
physiological and pathological processes, attempts were made to develop novel …
physiological and pathological processes, attempts were made to develop novel …
Reactive Sulfur Species in human diseases
M Iciek, A Bilska-Wilkosz, M Kozdrowicki… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Reactive sulfur species (RSS) have been recently recognized as redox
molecules no less important than reactive oxygen species or reactive nitrogen species. They …
molecules no less important than reactive oxygen species or reactive nitrogen species. They …
NSAIDs: Old acquaintance in the pipeline for cancer treatment and prevention─ Structural modulation, mechanisms of action, and bright future
S Ramos-Inza, AC Ruberte, C Sanmartin… - Journal of Medicinal …, 2021 - ACS Publications
The limitations of current chemotherapeutic drugs are still a major issue in cancer treatment.
Thus, targeted multimodal therapeutic approaches need to be strategically developed to …
Thus, targeted multimodal therapeutic approaches need to be strategically developed to …