The plasticity of mRNA translation during cancer progression and therapy resistance

L Fabbri, A Chakraborty, C Robert, S Vagner - Nature Reviews Cancer, 2021 - nature.com
Translational control of mRNAs during gene expression allows cells to promptly and
dynamically adapt to a variety of stimuli, including in neoplasia in response to aberrant …

RNA-binding proteins in tumor progression

H Qin, H Ni, Y Liu, Y Yuan, T Xi, X Li… - Journal of hematology & …, 2020 - Springer
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and
important biological functions. They are critical to maintain the transcriptome through post …

RNA-binding proteins in cancer: old players and new actors

B Pereira, M Billaud, R Almeida - Trends in cancer, 2017 - cell.com
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

Targeting an RNA-binding protein network in acute myeloid leukemia

E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee… - Cancer cell, 2019 - cell.com
RNA-binding proteins (RBPs) are essential modulators of transcription and translation
frequently dysregulated in cancer. We systematically interrogated RBP dependencies in …

RNA-binding proteins and cancer metastasis

S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia

A Laddach, SH Chng, R Lasrado, F Progatzky… - Nature …, 2023 - nature.com
Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

Cold shock proteins: from cellular mechanisms to pathophysiology and disease

JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …

Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells

J Lv, Y Zhou, N Zhou, Z Wang, J Chen… - Science translational …, 2023 - science.org
Weak immunogenicity of tumor cells is a root cause for the ultimate failure of
immunosurveillance and immunotherapy. Although tumor evolution can be shaped by …

N6‐methyladenosine‐modified lncRNA ARHGAP5‐AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma

J Liu, N Zhang, J Zeng, T Wang, Y Shen… - Clinical and …, 2022 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) ranks fourth among the malignancies leading
to cancer‐related deaths all around the world. It is increasingly evident that long non‐coding …

IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors

S Müller, N Bley, M Glaß, B Busch… - Nucleic acids …, 2018 - academic.oup.com
The oncofetal IGF2 mRNA binding proteins (IGF2BPs) are upregulated in most cancers but
their paralogue-specific roles in tumor cells remain poorly understood. In a panel of five …