Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners
T Muramatsu - The journal of biochemistry, 2016 - academic.oup.com
Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to
the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin …
the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin …
Cyclophilin–CD147 interactions: a new target for anti-inflammatory therapeutics
V Yurchenko, S Constant… - Clinical & …, 2010 - academic.oup.com
CD147 is a widely expressed plasma membrane protein that has been implicated in a
variety of physiological and pathological activities. It is best known for its ability to function as …
variety of physiological and pathological activities. It is best known for its ability to function as …
The glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via APOE/D
Elevated reactive oxygen species (ROS) induce the formation of lipids in neurons that are
transferred to glia, where they form lipid droplets (LDs). We show that glial and neuronal …
transferred to glia, where they form lipid droplets (LDs). We show that glial and neuronal …
CD147 immunoglobulin superfamily receptor function and role in pathology
The immunoglobulin superfamily member CD147 plays an important role in fetal, neuronal,
lymphocyte and extracellular matrix development. Here we review the current understanding …
lymphocyte and extracellular matrix development. Here we review the current understanding …
How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activity
GD Grass, BP Toole - Bioscience Reports, 2016 - portlandpress.com
Matrix metalloproteinases (MMPs) comprise a family of 23 zinc-dependent enzymes
involved in various pathologic and physiologic processes. In cancer, MMPs contribute to …
involved in various pathologic and physiologic processes. In cancer, MMPs contribute to …
Cancer-related issues of CD147
UH Weidle, W Scheuer, D Eggle… - Cancer genomics & …, 2010 - cgp.iiarjournals.org
CD147 is involved in many physiological functions, such as lymphocyte responsiveness,
spermatogenesis, implantation, fertilization and neurological functions at early stages of …
spermatogenesis, implantation, fertilization and neurological functions at early stages of …
The functional organisation of glia in the adult brain of Drosophila and other insects
TN Edwards, IA Meinertzhagen - Progress in neurobiology, 2010 - Elsevier
This review annotates and categorises the glia of adult Drosophila and other model insects
and analyses the developmental origins of these in the Drosophila optic lobe. The functions …
and analyses the developmental origins of these in the Drosophila optic lobe. The functions …
CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
W Schneiderhan, M Scheler, KH Holzmann, M Marx… - Gut, 2009 - gut.bmj.com
Background: CD147 (basigin, EMMPRIN) is a multifunctional, highly conserved glycoprotein
enriched in pancreatic ductal adenocarcinomas (PDACs) which is associated with poor …
enriched in pancreatic ductal adenocarcinomas (PDACs) which is associated with poor …
Extracellular matrix metalloproteinase inducer in brain ischemia and intracerebral hemorrhage
Increasing evidence from preclinical and clinical studies link neuroinflammation to
secondary brain injury after stroke, which includes brain ischemia and intracerebral …
secondary brain injury after stroke, which includes brain ischemia and intracerebral …
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
HR Shcherbata, AS Yatsenko, L Patterson… - The EMBO …, 2007 - embopress.org
Perturbation in the Dystroglycan (Dg)–Dystrophin (Dys) complex results in muscular
dystrophies and brain abnormalities in human. Here we report that Drosophila is an …
dystrophies and brain abnormalities in human. Here we report that Drosophila is an …