Global prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus: an updated systematic review and meta-analysis

EEL Cho, CZ Ang, J Quek, CE Fu, LKE Lim, ZEQ Heng… - Gut, 2023 - gut.bmj.com
Introduction Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver
disease, with type 2 diabetes mellitus (T2DM) as a major predictor. Insulin resistance and …

HOMA-IR as a predictor of health outcomes in patients with metabolic risk factors: a systematic review and meta-analysis

JG González-González, JR Violante-Cumpa… - High Blood Pressure & …, 2022 - Springer
Introduction There exists clinical interest in the following question: Is there an association
between HOMA-IR and the risk of developing metabolic diseases? Aims Assessing the …

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

E Isokuortti, Y Zhou, M Peltonen, E Bugianesi… - Diabetologia, 2017 - Springer
Abstract Aims/hypothesis Recent European guidelines for non-alcoholic fatty liver disease
(NAFLD) call for reference values for HOMA-IR. In this study, we aimed to determine:(1) the …

Lessons on drug development: a literature review of challenges faced in nonalcoholic fatty liver disease (NAFLD) clinical trials

JYS Chen, D Chua, CO Lim, WX Ho… - International Journal of …, 2022 - mdpi.com
NAFLD is the most common chronic liver disease worldwide, occurring in both obese and
lean patients. It can lead to life-threatening liver diseases and nonhepatic complications …

Non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome and their association with vascular risk

E Muzurović, DP Mikhailidis, C Mantzoros - Metabolism, 2021 - Elsevier
The prevalence of non-alcoholic fatty liver disease (NAFLD), one of the most common liver
diseases, is rising. About 25% of adults worldwide are probably affected by NAFLD. Insulin …

Metabolic score for insulin resistance is inversely related to incident advanced liver fibrosis in patients with non-alcoholic fatty liver disease

JH Lee, YJ Kwon, K Park, HS Lee, HK Park, JH Han… - Nutrients, 2022 - mdpi.com
We determined the relationships between metabolic score for IR (METS-IR), triglyceride-
glucose (TyG) index, and homeostatic model assessment for IR (HOMA-IR) and incident …

Comparison of the triglyceride glucose index and modified triglyceride glucose indices to predict nonalcoholic fatty liver disease in youths

K Song, G Park, HS Lee, M Lee, HI Lee, HS Choi… - The Journal of …, 2022 - Elsevier
Objective To assess the associations between the triglyceride glucose (TyG) index and
modified TyG indices with nonalcoholic fatty liver disease (NAFLD) and evaluate their ability …

Efficacy and safety of intragastric balloon (IGB) in non-alcoholic fatty liver disease (NAFLD): a comprehensive review and meta-analysis

S Chandan, BP Mohan, SR Khan, A Facciorusso… - Obesity Surgery, 2021 - Springer
Intragastric balloon (IGB) therapy has shown efficacy in weight loss but its role in NAFLD
remains unknown. We conducted a systematic review and meta-analysis to evaluate the …

An untargeted metabolomics approach reveals further insights of Lycium barbarum polysaccharides in high fat diet and streptozotocin-induced diabetic rats

H Xia, H Tang, F Wang, X Yang, Z Wang, H Liu… - Food Research …, 2019 - Elsevier
Lycium barbarum polysaccharide (LBP), as one bioactive macromolecular abstracted from
goji berry, has shown an abundance of potential function. The present study aimed to …

Combination of asprosin and adiponectin as a novel marker for diagnosing non-alcoholic fatty liver disease

F Ke, G Xue, X Jiang, F Li, X Lai, M Zhang, Y Shen… - Cytokine, 2020 - Elsevier
Background and objective Patients with non-alcoholic fatty liver disease (NAFLD) have
insulin resistance and are at an increased risk of diabetes. Recent evidence suggests that …