Bacteria must divide to increase in number and colonize their niche. Binary fission is the
most widespread means of bacterial cell division, but even this relatively simple mechanism …

The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …

Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

The lytic transglycosylases (LTs) are bacterial enzymes that catalyze the non-hydrolytic
cleavage of the peptidoglycan structures of the bacterial cell wall. They are not catalysts of …

Bacteria account for 1000-fold more biomass than humans. They vary widely in shape and
size. The morphological diversity of bacteria is due largely to the different peptidoglycan …

Tol-Pal is a multiprotein system present in the envelope of Gram-negative bacteria.
Inactivation of this widely conserved machinery compromises the outer membrane (OM) …

Long non-coding RNAs (lncRNAs) have been identified as important regulatory factors of
gene expression in eukaryotic species, such as Homo sapiens, Arabidopsis thaliana, and …

The peptidoglycan sacculus is a net-like polymer that surrounds the cytoplasmic membrane
in most bacteria. It is essential to maintain the bacterial cell shape and protect from turgor …

During infection of bladder epithelial cells, uropathogenic Escherichia coli (UPEC) can stop
dividing and grow into highly filamentous forms. Here, we find that some filaments of E. coli …

The peptidoglycan cell wall is a predominant structure of bacteria, determining cell shape
and supporting survival in diverse conditions. Peptidoglycan is dynamic and requires …