Diffusion MRI of the breast: Current status and future directions

M Iima, M Honda, EE Sigmund… - Journal of Magnetic …, 2020 - Wiley Online Library
Diffusion‐weighted imaging (DWI) is increasingly being incorporated into routine breast MRI
protocols in many institutions worldwide, and there are abundant breast DWI indications …

The 2019 mathematical oncology roadmap

RC Rockne, A Hawkins-Daarud, KR Swanson… - Physical …, 2019 - iopscience.iop.org
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …

A review of mathematical models for tumor dynamics and treatment resistance evolution of solid tumors

A Yin, DJAR Moes, JGC van Hasselt… - CPT …, 2019 - Wiley Online Library
Increasing knowledge of intertumor heterogeneity, intratumor heterogeneity, and cancer
evolution has improved the understanding of anticancer treatment resistance. A better …

Prior to initiation of chemotherapy, can we predict breast tumor response? Deep learning convolutional neural networks approach using a breast MRI tumor dataset

R Ha, C Chin, J Karcich, MZ Liu, P Chang… - Journal of digital …, 2019 - Springer
We hypothesize that convolutional neural networks (CNN) can be used to predict
neoadjuvant chemotherapy (NAC) response using a breast MRI tumor dataset prior to …

In silico modelling of cancer nanomedicine, across scales and transport barriers

NR Stillman, M Kovacevic, I Balaz… - NPJ Computational …, 2020 - nature.com
Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …

Integrating mechanism-based modeling with biomedical imaging to build practical digital twins for clinical oncology

C Wu, G Lorenzo, DA Hormuth, EABF Lima… - Biophysics …, 2022 - pubs.aip.org
Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …

Mathematical models of tumor cell proliferation: A review of the literature

AM Jarrett, EABF Lima, DA Hormuth… - Expert review of …, 2018 - Taylor & Francis
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …

Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation

DA Hormuth, KA Al Feghali, AM Elliott, TE Yankeelov… - Scientific reports, 2021 - nature.com
High-grade gliomas are an aggressive and invasive malignancy which are susceptible to
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …

[HTML][HTML] Role of magnetic resonance imaging in detection of pathologic complete remission in breast cancer patients treated with neoadjuvant chemotherapy: a meta …

YL Gu, SM Pan, J Ren, ZX Yang, GQ Jiang - Clinical Breast Cancer, 2017 - Elsevier
Pathologic complete remission after neoadjuvant chemotherapy has a role in guiding the
management of breast cancer. The present meta-analysis examined the accuracy of contrast …

Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth

G Lorenzo, TJR Hughes… - Proceedings of the …, 2019 - National Acad Sciences
Prostate cancer and benign prostatic hyperplasia are common genitourinary diseases in
aging men. Both pathologies may coexist and share numerous similarities, which have …