Originally, the peroxisomal targeting signal 1 (PTS1) was defined as a tripeptide at the C-
terminus of proteins prone to be imported into the peroxisomal matrix. The corresponding …

Lipid droplets (LDs) and peroxisomes are central players in cellular lipid homeostasis: some
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …

Peroxisomes are unique among the organelles of the endomembrane system. Unlike other
organelles that derive most if not all of their proteins from the ER (endoplasmic reticulum) …

Reactive oxygen species (ROS) are at once unsought by-products of metabolism and critical
regulators of multiple intracellular signaling cascades. In nonphotosynthetic eukaryotic cells …

▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …

To specify the C-terminal peroxisome targeting signal type 1 (PTS1) and the N-terminal
PTS2 for higher plants, a maximum number of plant cDNAs and expressed sequence tags …

The importance of peroxisomes in lipid metabolism is now well established and
peroxisomes contain approximately 60 enzymes involved in these lipid metabolic pathways …

Peroxisomal matrix proteins have to be imported into their target organelle post-
translationally. The major translocation pathway depends on a C-terminal targeting signal …

Using two-dimensional electrophoresis, we have recently identified in human
bronchoalveolar lavage fluid a novel protein, termed B166, with a molecular mass of 17 kDa …

The proper distribution of proteins between the cytosol and various membrane-bound
compartments is crucial for the functionality of eukaryotic cells. This requires the cooperation …