How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children
DT Teachey, D O'Connor - Blood, The Journal of the American …, 2020 - ashpublications.org
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that has
historically been associated with a very poor prognosis. Nevertheless, despite a lack of …
historically been associated with a very poor prognosis. Nevertheless, despite a lack of …
IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?
M Stanulla, H Cavé, AV Moorman - Blood, The Journal of the …, 2020 - ashpublications.org
Improved personalized adjustment of primary therapy to the perceived risk of relapse by
using new prognostic markers for treatment stratification may be beneficial to patients with …
using new prognostic markers for treatment stratification may be beneficial to patients with …
Genotype-specific minimal residual disease interpretation improves stratification in pediatric acute lymphoblastic leukemia
Purpose Minimal residual disease (MRD) and genetic abnormalities are important risk
factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize …
factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize …
Global efforts toward the cure of childhood acute lymphoblastic leukaemia
Improvements in risk-directed treatment and supportive care, together with increased
reliance on both national and international collaborative studies, have made childhood …
reliance on both national and international collaborative studies, have made childhood …
[HTML][HTML] Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and …
Background High hyperdiploidy is the most common genetic subtype of childhood acute
lymphoblastic leukaemia and is associated with a good outcome. However, some patients …
lymphoblastic leukaemia and is associated with a good outcome. However, some patients …
[HTML][HTML] Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial
C Schwab, RE Cranston, SL Ryan, E Butler… - Leukemia, 2023 - nature.com
Incorporating genetics into risk-stratification for treatment of childhood B-progenitor acute
lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about …
lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about …
[HTML][HTML] Advances in B-cell precursor acute lymphoblastic leukemia genomics
C Schwab, CJ Harrison - Hemasphere, 2018 - journals.lww.com
In childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), cytogenetic
abnormalities remain important diagnostic and prognostic tools. A number of well …
abnormalities remain important diagnostic and prognostic tools. A number of well …
DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a …
SN Nielsen, K Grell, J Nersting, J Abrahamsson… - The Lancet …, 2017 - thelancet.com
Background Adjustment of mercaptopurine and methotrexate maintenance therapy of acute
lymphoblastic leukaemia by leucocyte count is confounded by natural variations. Cytotoxicity …
lymphoblastic leukaemia by leucocyte count is confounded by natural variations. Cytotoxicity …
Label‐free leukemia monitoring by computer vision
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. While there are
a number of well‐recognized prognostic biomarkers at diagnosis, the most powerful …
a number of well‐recognized prognostic biomarkers at diagnosis, the most powerful …
[HTML][HTML] BCR-ABL1-like acute lymphoblastic leukaemia: From bench to bedside
JM Boer, ML den Boer - European Journal of Cancer, 2017 - Elsevier
Acute lymphoblastic leukaemia (ALL) occurs in approximately 1: 1500 children and is less
frequently found in adults. The most common immunophenotype of ALL is the B cell lineage …
frequently found in adults. The most common immunophenotype of ALL is the B cell lineage …