Studies of bioactive lipids in general and sphingolipids in particular have intensified over the
past several years, revealing an unprecedented and unanticipated complexity of the …

Fluconazole (FLC) tolerant phenotypes in Candida species contribute to persistent
candidemia and the emergence of FLC resistance. Therefore, making FLC fungicidal and …

Fluconazole (FLC) is widely used to prevent and treat invasive fungal infections. However,
FLC is a fungistatic agent, allowing clinical FLC-susceptible isolates to tolerate FLC. Making …

Artificial sweeteners (AS) are the emerging contaminants with potential toxicity to living
organisms. The effects of AS to soil typical invertebrates have not been revealed. In this …

Emerging studies of bioactive lipids have made many exciting discoveries in recent years.
Sphingolipids and their metabolites perform a wide variety of cellular functions beyond …

Modelling can provide intellectual frameworks that are necessary to translate data into
knowledge. Mathematical modelling has played an important role in many applications …

The concept of ageing is one that has intrigued mankind since the beginning of time and is
now more important than ever as the incidence of age-related disorders is increasing in our …

Introduction: Extrusion of azoles from the cell, mediated by an efflux pump Cdr1, is one of the
most frequently used strategies for developing azole resistance in pathogenic fungi. The …

Target of rapamycin complex 1 (TORC1) is an important regulator of various signaling
pathways. It can control cell growth and development by integrating multiple signals from …

Sphingolipids are involved in cell signaling and metabolic pathways, and their metabolites
play a critical role in host defense against intracellular pathogens. Here, we review the …