The difunctionalizative trifluoromethylation of unsaturated C− C bonds is a highly useful and
efficient method for the synthesis of trifluoromethyl compounds with attractive architectures …

Graphene oxide (GO), as a metal-free and readily available carbocatalyst, has been
extensively applied in catalytic organic transformations. This minireview aims to give an …

Radical spirocyclization via dearomatization has emerged as an attractive strategy for the
rapid synthesis of structurally diverse spiro molecules. We report the use of electrochemistry …

Abstract A novel series of 4-(3-(difluorophenyl)-5-(dimethoxyphenyl)-4, 5-dihydropyrazol-1-
yl) benzenesulfonamides 1–8 were designed since sulfonamide and pyrazoline …

A transition-metal-and oxidant-free electrochemical strategy for radical fluoroalkylation of
vinyl azides was developed. The reaction was carried out under mild conditions by using …

Fluorinated enol silanes are broadly useful in various synthetic transformations such as
Mukaiyama aldol, Michael, and Mannich reactions. However, previous methods to these …

This account describes our recent progress on the strategic incorporation of fluorine and
organofluorine moieties into new-generation taxoid anticancer agents for medicinal …

Abstract A series of 1, 2, 3-triazole analogues as novel fat mass and obesity-associated
protein (FTO) inhibitors were synthesised in this study. Among all 1, 2, 3-triazoles …

Carbonic anhydrase (CA) is a metalloenzyme that catalyzes the interconversion between
carbon dioxide and water and dissociated ions of carbonic acid. In addition, CA performs …

The demand for practical methods for the synthesis of novel fluoroalkyl molecules is
increasing owing to their diverse applications. Our group has achieved efficient …