Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

Inorganic phosphate (Pi) is essential for signal transduction and cell metabolism, and is also
an essential structural component of the extracellular matrix of the skeleton. Pi is sensed in …

Phosphorus is a macronutrient taken up by cells as inorganic phosphate (Pi). How cells
sense cellular Pi levels is poorly characterized. Here, we report that SPX domains—which …

Inorganic phosphate (Pi) is one of the essential molecules for life. However, little is known
about intracellular Pi metabolism and signalling in animal tissues. Following the observation …

CRISPR knockout (KO) screens have identified host factors regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we conducted a meta …

Microglia are macrophages that colonize the brain during development to establish a
resident population of professional phagocytes that protect against invading pathogens and …

In mammals, phosphate balance is maintained by influx and efflux via the intestines,
kidneys, bone, and soft tissue, which involves multiple sodium/phosphate (Na+/Pi) …

Inorganic phosphate (Pi) is an abundant element in the body and is essential for a wide
variety of key biological processes. It plays an essential role in cellular energy metabolism …

Biomineralization is the process by which organisms produce mineralized tissues. This
crucial process makes possible the rigidity and flexibility that the skeleton needs for …

Synthetic anion receptors are increasingly being explored for the transport of anions across
lipid membranes because of their potential therapeutic applications. A considerable amount …