Hearing Loss in Adults | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Common causes of hearing loss in humans-exposure to loud noise or ototoxic drugs and
aging-often damage sensory hair cells, reflected as elevated thresholds on the clinical …

Tinnitus, reduced sound-level tolerance, and difficulties hearing in noisy environments are
the most common complaints associated with sensorineural hearing loss in adult …

The classic view of sensorineural hearing loss has been that the primary damage targets are
hair cells and that auditory nerve loss is typically secondary to hair cell degeneration …

Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies.
In these animal models, the disorder is characterized by a reduction in amplitude of wave I of …

Abstract Models of the human auditory periphery range from very basic functional
descriptions of auditory filtering to detailed computational models of cochlear mechanics …

The purpose of this study was to test the hypothesis that listeners with frequent exposure to
loud music exhibit deficits in suprathreshold auditory performance consistent with cochlear …

Hidden hearing loss (HHL) is a recently described auditory neuropathy believed to
contribute to speech discrimination and intelligibility deficits in people with normal …

Understanding the biology of the previously underappreciated sensitivity of cochlear
synapses to noise insult, and its clinical consequences, is becoming a mission for a growing …