Immunosensors—principles and applications to clinical chemistry

PB Luppa, LJ Sokoll, DW Chan - Clinica chimica acta, 2001 - Elsevier
Introduction: Immunosensors are affinity ligand-based biosensor solid-state devices in which
the immunochemical reaction is coupled to a transducer. The fundamental basis of all …

Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition

JM McDonnell - Current opinion in chemical biology, 2001 - Elsevier
With the introduction of new instruments and improved sensor chip chemistries, surface
plasmon resonance (SPR) is finding new applications for molecular interaction studies. Easy …

Antimicrobial drug discovery through bacteriophage genomics

J Liu, M Dehbi, G Moeck, F Arhin, P Bauda… - Nature …, 2004 - nature.com
Over evolutionary time bacteriophages have developed unique proteins that arrest critical
cellular processes to commit bacterial host metabolism to phage reproduction. Here, we …

[HTML][HTML] Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor

OJS Macleod, AD Cook, H Webb, M Crow… - Nature …, 2022 - nature.com
African trypanosomes are extracellular pathogens of mammals and are exposed to the
adaptive and innate immune systems. Trypanosomes evade the adaptive immune response …

Real-Time Monitoring of the Interactions of Two-Stranded de Novo Designed Coiled-Coils:  Effect of Chain Length on the Kinetic and Thermodynamic Constants of …

G De Crescenzo, JR Litowski, RS Hodges… - Biochemistry, 2003 - ACS Publications
We have de novo designed a heterodimeric coiled-coil formed by two peptides as a
capture/delivery system that can be used in applications such as affinity tag purification …

Dual interactions of the translational repressor Paip2 with poly (A) binding protein

K Khaleghpour, A Kahvejian… - … and cellular biology, 2001 - Taylor & Francis
The cap structure and the poly (A) tail of eukaryotic mRNAs act synergistically to enhance
translation. This effect is mediated by a direct interaction of eukaryotic initiation factor 4G and …

Paip1 interacts with poly (A) binding protein through two independent binding motifs

G Roy, G De Crescenzo, K Khaleghpour… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract The 3′ poly (A) tail of eukaryotic mRNAs plays an important role in the regulation
of translation. The poly (A) binding protein (PABP) interacts with eukaryotic initiation factor …

[HTML][HTML] On the use of surface plasmon resonance biosensing to understand IgG-FcγR interactions

C Forest-Nault, J Gaudreault, O Henry… - International Journal of …, 2021 - mdpi.com
Surface plasmon resonance (SPR)-based optical biosensors offer real-time and label-free
analysis of protein interactions, which has extensively contributed to the discovery and …

Advanced biosensors for nanomaterial-based detection of transforming growth factor alpha and beta, a class of major polypeptide regulators

S Gaba, U Jain - International Journal of Biological Macromolecules, 2023 - Elsevier
Transforming growth factors (TGFs) regulate several cellular processes including,
differentiation, growth, migration, extracellular matrix production, and apoptosis. TGF alpha …

A mechanism of translational repression by competition of Paip2 with eIF4G for poly (A) binding protein (PABP) binding

MM Karim, YV Svitkin, A Kahvejian… - Proceedings of the …, 2006 - National Acad Sciences
The eukaryotic mRNA 3′ poly (A) tail and the 5′ cap cooperate to synergistically enhance
translation. This interaction is mediated by the cap-binding protein eIF4E, the poly (A) …