Candida auris Genetics and Emergence

A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare …

S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …

Confirmation of fifth Candida auris clade by whole genome sequencing

B Spruijtenburg, H Badali, M Abastabar… - Emerging microbes & …, 2022 - Taylor & Francis
Candida auris has emerged globally as a multidrug-resistant pathogen causing outbreaks in
health care facilities. Whole genome sequencing (WGS) analysis has identified four major …

[HTML][HTML] Potential fifth clade of Candida auris, Iran, 2018

NA Chow, T de Groot, H Badali… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
Four major clades of Candida auris have been described, and all infections have clustered
in these 4 clades. We identified an isolate representative of a potential fifth clade, separated …

[HTML][HTML] The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris

JM Rybak, CA Cuomo, PD Rogers - Current opinion in microbiology, 2022 - Elsevier
Highlights•C. auris exhibits resistance to multiple antifungal agents and represents a public
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …

The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

Is the superbug fungus really so scary? A systematic review and meta-analysis of global epidemiology and mortality of Candida auris

J Chen, S Tian, X Han, Y Chu, Q Wang, B Zhou… - BMC Infectious …, 2020 - Springer
Background Candida auris is a new pathogen called “superbug fungus” which caused panic
worldwide. There are no large-scale epidemiology studies by now, therefore a systematic …

Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance

H Carolus, S Pierson, JF Muñoz, A Subotić, RB Cruz… - MBio, 2021 - Am Soc Microbiol
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …

Candida auris and multidrug resistance: Defining the new normal

SR Lockhart - Fungal Genetics and Biology, 2019 - Elsevier
Candida auris is an emerging species of yeast characterized by colonization of skin,
persistence in the healthcare environment, and antifungal resistance. C. auris was first …

Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases

N Geremia, P Brugnaro, M Solinas, C Scarparo… - Healthcare, 2023 - mdpi.com
Candida auris is considered to be an emerging fungal pathogen and is related to high
mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and …