Lipoprotein lipase (LPL) is a rate-limiting enzyme for hydrolysing circulating triglycerides
(TG) into free fatty acids that are taken up by peripheral tissues. Postprandial LPL activity …

Summary ANGPTL3, ANGPTL4 and ANGPTL8 together ensure that triglycerides from
triglyceride-rich lipoproteins are adequately distributed during different physiological …

Lipasin (also known as C19ORF80, RIFL, ANGPTL8 and betatrophin) is a newly discovered
circulating factor that regulates lipid metabolism and promotes pancreatic β-cell proliferation …

Recently, it was reported that angiopoietin-like protein 8 (ANGPTL8) was the long-sought"
betatrophin" that could control pancreatic beta cell proliferation. However, studies of …

Context: Betatrophin is a secreted protein recently involved in β-cell replication with a
potential role in type 2 diabetes mellitus (T2D). Objective: The aim of the present study was …

OBJECTIVE Betatrophin, a newly identified hormone, has been recently characterized as a
potent stimulator that increases the production and expansion of insulin-secreting β-cells in …

Hypothyroidism is often associated with elevated serum levels of total cholesterol, LDL-C
and triglycerides. Thyroid hormone (TH) affects the production, clearance and transformation …

Context: Betatrophin has recently attracted increasing interests as a potential β-cell
regenerative therapy in diabetes. However, differences in betatrophin profiles in patients …

Betatrophin/ANGPTL8 is a newly identified hormone produced in liver and adipose tissue
that has been shown to be induced as a result of insulin resistance and regulates lipid …

Betatrophin has recently been described as a key hormone to stimulate beta‐cell mass
expansion in response to insulin resistance and obesity in mice. The finding has generated …