The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Proteins are involved in many biological processes. Misfolded, truncated, or mutated
proteins as well as over-or underexpressed proteins have been implicated in many …

CRISPR-based nucleic-acid detection is an emerging technology for molecular diagnostics.
However, these methods generally require several hours and could cause amplification …

The evolutionary origins of neurons remain unknown. Although recent genome data of
extant early-branching animals have shown that neural genes existed in the common …

Nanopores are key in portable sequencing and research given their ability to transport
elongated DNA or small bioactive molecules through narrow transmembrane channels …

Digital bioassays based on single-molecule enzyme reactions represent a new class of
bioanalytical methods that enable the highly sensitive detection of biomolecules in a …

Sphingomyelin (SM) has been proposed to form cholesterol-dependent raft domains and
sphingolipid domains in the plasma membrane (PM). How SM contributes to the formation …

The development of bioassays with high sensitivity has received significant attention.
Enormous efforts based on a variety of signal amplification techniques have been made for …

Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

Digital PCR (dPCR) is a revolutionary technique to precisely quantify nucleic acids. For its
high sensitivity and specificity, this technique has been widely replicated worldwide. To …