Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …

In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Multidrug resistance (MDR) represents a global threat to health. Here, we used whole
genome sequencing to characterise Pseudomonas aeruginosa MDR clinical isolates from a …

When considering the interactions between bacteriophages and their host, the issue of
phage-resistance emergence is a key element in understanding the ecological impact of …

The diversification of microbial populations may be driven by many factors including
adaptation to distinct ecological niches and barriers to recombination. We examined the …

Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …

What are bacteria doing during “reversible attachment,” the period of transient surface
attachment when they initially engage a surface, besides attaching themselves to the …

Outbreaks of virulent and/or drug-resistant bacteria have a significant impact on human
health and major economic consequences. Genomic islands (GIs; defined as clusters of …