Sodium‐glucose co‐transporter‐2 inhibitors in patients with type 2 diabetes: barriers and solutions for improving uptake in routine clinical practice

K Khunti, S Jabbour, X Cos, S Mudaliar… - Diabetes, Obesity …, 2022 - Wiley Online Library
Recent advances in type 2 diabetes (T2D) research have highlighted the benefits of sodium‐
glucose co‐transporter‐2 (SGLT‐2) inhibitors, including cardiovascular and renal protection …

The new role of SGLT2 inhibitors in the management of heart failure: current evidence and future perspective

S Muscoli, F Barillà, R Tajmir, M Meloni, D Della Morte… - Pharmaceutics, 2022 - mdpi.com
The sodium-glucose transporter 2 inhibitors (SGLT2i) are a relatively new class of
medication used in the management of type 2 diabetes. Recent clinical trials and research …

Dapagliflozin: a review in symptomatic heart failure with reduced ejection fraction

HA Blair - American Journal of Cardiovascular Drugs, 2021 - Springer
Abstract Dapagliflozin [Farxiga®(USA); Forxiga®(EU)], a sodium–glucose cotransporter 2
(SGLT2) inhibitor, was recently approved in the USA and the EU for the treatment of adults …

[HTML][HTML] SGLT2 Inhibitor: an Emerging Pillar in Heart Failure Therapeutics?

MA Munteanu, S Swarnkar, RI Popescu, A Lungu… - Maedica, 2023 - ncbi.nlm.nih.gov
Heart failure (HF) is a worldwide pandemic that affects at least 26 million people and is
becoming more prevalent. Heart failure health expenditures are substantial and will …

Surprises in cardiology: Efficacy of gliflozines in heart failure even in the absence of diabetes

A Bragagni, F Piani, C Borghi - European Heart Journal …, 2021 - academic.oup.com
It is now well-established that the therapy of type II diabetes mellitus has undergone a
radical change in the past 15 years: countless innovative drugs, such as SGLT2I, able to …

[HTML][HTML] The effects of sodium-glucose cotransporter-2 inhibitors (SLGT-2i) on cardiovascular and renal outcomes in non-diabetic patients: A systematic review

SG Ravindran, M Kakarla, MA Gambo, MY Salama… - Cureus, 2022 - ncbi.nlm.nih.gov
Globally, cardiovascular disease (CVD) and chronic kidney disease (CKD) are the leading
causes of mortality. Despite medical advances, these illnesses are still underdiagnosed and …

[HTML][HTML] Long-term efficacy of sodium-glucose cotransporter 2 inhibitor therapy in preventing atrial fibrillation recurrence after catheter ablation in type 2 diabetes …

HT Liu, HT Wo, PC Chang, HL Lee, MS Wen, CC Chou - Heliyon, 2023 - cell.com
Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce new-onset atrial
fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We aimed to determine the …

[HTML][HTML] Overview of sodium-glucose Co-transporter 2 (SGLT2) inhibitors for the treatment of non-diabetic heart failure patients

I Balan, T Khayo, S Sultanova, Y Lomakina - Cureus, 2021 - ncbi.nlm.nih.gov
Heart failure (HF) is a clinical syndrome that results from any structural or functional
impairment of ventricular filling or ejection of blood, and results in low life quality and …

[HTML][HTML] SGLT2 inhibitors: a new pillar of the heart failure regimen

T DeSa, T Gong - Reviews in Cardiovascular Medicine, 2021 - imrpress.com
Initially intended as an adjunct treatment for type 2 diabetes mellitus (T2DM), SGLT2-
inhibitors (SGLT2i) have transformed into an unexpected pillar of the heart failure (HF) …

[HTML][HTML] Effect of ertugliflozin on renal function and cardiovascular outcomes in patients with type 2 diabetes mellitus: A systematic review and meta-analysis

Q Cheng, S Zou, C Feng, C Xu, Y Zhao, X Shi, M Sun - Medicine, 2023 - journals.lww.com
Background: The global prevalence of type 2 diabetes mellitus (T2DM) is growing yearly.
The efficacy of ertugliflozin (ERT), a recently licensed anti-diabetic drug, has been widely …