The spleen is the main filter for blood-borne pathogens and antigens, as well as a key organ
for iron metabolism and erythrocyte homeostasis. Also, immune and hematopoietic functions …

Following anti-malarial drug treatment asexual malaria parasite killing and clearance
appear to be first order processes. Damaged malaria parasites in circulating erythrocytes …

Malaria and the Spleen In this report, patients living in a malaria-endemic area underwent
trauma-related splenectomy. In these asymptomatic patients who were naturally infected …

Background Severe malaria is a major cause of childhood death and often the main reason
for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established …

Successful control of falciparum malaria depends greatly on treatment with artemisinin
combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged …

Artemisinin and its derivatives have become essential components of antimalarial treatment.
These plant-derived peroxides are unique among antimalarial drugs in killing the young …

We investigate connections between single-cell mechanical properties and subcellular
structural reorganization from biochemical factors in the context of two distinctly different …

Background In the treatment of severe malaria, intravenous artesunate is more rapidly acting
than intravenous quinine in terms of parasite clearance, is safer, and is simpler to …

Clinical manifestations of Plasmodium falciparum infection are induced by the asexual
stages of the parasite that develop inside red blood cells (RBCs). Because splenic …

Summary Background Artemisinin-resistant Plasmodium falciparum has been reported in
Pailin, western Cambodia, detected as a slow parasite clearance rate in vivo. Emergence of …