Primary cancer cell lines are ex vivo cell cultures originating from resected tissues during
biopsies and surgeries. Primary cell cultures are objects of intense research due to their …

Conventional tumor models have critical shortcomings in that they lack the complexity of the
human stroma. The heterogeneous stroma is a central compartment of the tumor …

Hepatocytes are the central cells of the liver responsible for its metabolic function. As such,
they form a uniquely polarized epithelium, in which two or more hepatocytes contribute …

The ability to engineer biologically viable hepatocytes and tissue matrices with long-term
functional maintenance has attracted considerable interest in the fields of hepatocyte …

Acute cellular rejection (ACR) after liver transplantation (LT) goes along with allograft
dysfunction, which is diagnosed by liver biopsy and concomitant histological analysis …

Hepatic steatosis is a consequence of distorted lipid storage and plays a vital role in the
pathogenesis of nonalcoholic fatty liver disease (NAFLD). This study aimed to explore the …

Background: Toxoplasma gondii with widespread distribution infects over one third of
human populations in the world and can cause serious life-threatening diseases especially …

Primary hepatocytes are widely used in basic research on liver diseases and for toxicity
testing in vitro. The two-step collagenase perfusion procedure for primary hepatocyte …

In vitro validation of therapeutic and recombinant proteins expressed from transgenic
chickens is limited by the co-culture of fibroblasts. Here, we present a protocol for isolating …

Although common in the commercial turkey industry, concurrent use of two or more drugs in
the same feed can result in drug-drug interactions that may impact drug clearance …