Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue
(BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat …

Single-cell sequencing technologies have revealed an unexpectedly broad repertoire of
cells required to mediate complex functions in multicellular organisms. Despite the multiple …

Brown adipose tissue plays a central role in the regulation of the energy balance by
expending energy to produce heat. NAD+-dependent deacylase sirtuins have widely been …

Cachexia is a complex tissue-wasting syndrome characterized by inflammation,
hypermetabolism, increased energy expenditure, and anorexia. Browning of white adipose …

Adipocytes play an essential role in maintaining energy homeostasis in mammals. The
primary function of white adipose tissue (WAT) is to store energy; for brown adipose tissue …

Milk fat is the most important and energy-rich substance in milk, and its content and
composition are important reference elements in the evaluation of milk quality. However, the …

Alterations in iron status have frequently been associated with obesity and other metabolic
disorders. The hormone hepcidin stands out as a key regulator in the maintenance of iron …

Simple Summary Despite the therapeutic advances, lung cancer is the most dangerous
cancer with poor 5-year survival rate due to metastasis and recurrence. Accumulated …

Cutaneous wound healing requires intricate synchronization of several key processes.
Among them, local nerve regeneration is known to be vitally important for proper repair …

The established role of ATP-responsive P2X7 receptor in inflammatory, neurodegenerative,
and immune diseases is now expanding to include several aspects of metabolic …