Cytokines play crucial roles in coordinating the activities of innate and adaptive immune
systems. In response to pathogen recognition, innate immune cells secrete cytokines that …

Abstract γδ T cells represent a small population of overall T lymphocytes (0.5–5%) and have
variable tissue distribution in the body. γδ T cells can perform complex functions, such as …

Summary Interleukin-12 (IL-12) and IL-23 are heterodimeric cytokines that are produced by
antigen-presenting cells to regulate the activation and differentiation of lymphocytes, and …

How defined microbes influence the skin immune system remains poorly understood. Here
we demonstrate that Corynebacteria, dominant members of the skin microbiota, promote a …

Purpose To analyse intraocular cytokine levels and prevalence of intraocular antiretinal
antibodies (ARA s) in patients with retinitis pigmentosa (RP), age‐related macular …

Dermal IL-17-producing γδT cells have a critical role in skin inflammation. However, their
development and peripheral regulation have not been fully elucidated. Here we …

The importance of IL‐23 and its specific receptor, IL‐23R, in the pathogenesis of several
chronic inflammatory diseases has been established, but the underlying pathological …

Increasing evidences have pointed out the relevance of natural killer (NK) cells in organ-
specific and systemic autoimmune diseases. NK cells bear a plethora of activating and …

Abstract γδ T lymphocytes are programmed into distinct IFN-γ–producing CD27+(γδ27+)
and IL-17–producing CD27−(γδ27−) subsets that play key roles in protective or pathogenic …

Importance Psoriasis, psoriatic arthritis, and uveitis are inflammatory disorders with
significant overlap in their inflammatory pathways. Limited evidence is available about the …