Inflammation balance in skeletal muscle damage and repair
H Tu, YL Li - Frontiers in immunology, 2023 - frontiersin.org
Responding to tissue injury, skeletal muscles undergo the tissue destruction and
reconstruction accompanied with inflammation. The immune system recognizes the …
reconstruction accompanied with inflammation. The immune system recognizes the …
Macrophage involvement in aging-associated skeletal muscle regeneration
CY Cui, L Ferrucci, M Gorospe - Cells, 2023 - mdpi.com
The skeletal muscle is a dynamic organ composed of contractile muscle fibers, connective
tissues, blood vessels and nerve endings. Its main function is to provide motility to the body …
tissues, blood vessels and nerve endings. Its main function is to provide motility to the body …
[HTML][HTML] Age-associated inflammation and implications for skeletal muscle responses to exercise
Aging is associated with profound alterations in skeletal muscle, including loss of muscle
mass and function, local inflammation, altered mitochondrial physiology, and attenuated …
mass and function, local inflammation, altered mitochondrial physiology, and attenuated …
Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis
Tissue fibrosis affects multiple organs and involves a master-regulatory role of macrophages
which respond to an initial inflammatory insult common in all forms of fibrosis. The recently …
which respond to an initial inflammatory insult common in all forms of fibrosis. The recently …
DPPIV+ fibro-adipogenic progenitors form the niche of adult skeletal muscle self-renewing resident macrophages
F Babaeijandaghi, N Kajabadi, R Long… - Nature …, 2023 - nature.com
Adult tissue-resident macrophages (RMs) are either maintained by blood monocytes or
through self-renewal. While the presence of a nurturing niche is likely crucial to support the …
through self-renewal. While the presence of a nurturing niche is likely crucial to support the …
Periodontal disease as a model to study chronic inflammation in aging
M Bertolini, D Clark - Geroscience, 2024 - Springer
Periodontal disease is a chronic inflammatory condition that results in the destruction of the
teeth supporting tissues, eventually leading to the loss of teeth and reduced quality of life. In …
teeth supporting tissues, eventually leading to the loss of teeth and reduced quality of life. In …
Mineralocorticoid receptor promotes cardiac macrophage inflammaging
D Fraccarollo, R Geffers, P Galuppo… - Basic Research in …, 2024 - Springer
Inflammaging, a pro-inflammatory status that characterizes aging and primarily involving
macrophages, is a master driver of age-related diseases. Mineralocorticoid receptor (MR) …
macrophages, is a master driver of age-related diseases. Mineralocorticoid receptor (MR) …
The role of macrophage populations in skeletal muscle insulin sensitivity: Current understanding and implications
MK Lee, H Ryu, JY Van, MJ Kim, HH Jeong… - International Journal of …, 2023 - mdpi.com
Insulin resistance is a crucial factor in the development of type 2 diabetes mellitus (T2DM)
and other metabolic disorders. Skeletal muscle, the body's largest insulin-responsive tissue …
and other metabolic disorders. Skeletal muscle, the body's largest insulin-responsive tissue …
Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …
and healthcare expenditures. It is now well established that diabetes is characterized by a …
The roles of miRNAs in adult skeletal muscle satellite cells
PJ Koopmans, A Ismaeel, K Goljanek-Whysall… - Free Radical Biology …, 2023 - Elsevier
Satellite cells are bona fide muscle stem cells that are indispensable for successful post-
natal muscle growth and regeneration after severe injury. These cells also participate in …
natal muscle growth and regeneration after severe injury. These cells also participate in …