CD38 is a molecule that can act as an enzyme, with NAD-depleting and intracellular
signaling activity, or as a receptor with adhesive functions. CD38 can be found expressed …

Cellular recognition of microbial DNA is an evolutionarily conserved mechanism by which
the innate immune system detects pathogens. Cyclic GMP-AMP synthase (cGAS) and its …

The rapid detection of microbial agents is essential for the effective initiation of host defence
mechanisms against infection. Understanding how cells detect cytosolic DNA to trigger …

Although cancer chemotherapy has historically been considered immune suppressive, it is
now accepted that certain chemotherapies can augment tumor immunity. The recent …

Recently, the potential use of cold atmospheric pressure plasma (CAP) in cancer treatment
has gained increasing interest. Especially the enhanced selective killing of tumor cells …

RAD51, a multifunctional protein, plays a central role in DNA replication and homologous
recombination repair, and is known to be involved in cancer development. We identified a …

Mounting scientific evidence over decades has established that atherosclerosis is a chronic
inflammatory disorder. Among the potentially critical sources of vascular inflammation during …

Chronic Inflammation in tumor microenvironments is not only associated with various stages
of tumor development, but also has significant impacts on tumor immunity and …

Mesenchymal stem cells (MSCs) are multipotent tissue stem cells that differentiate into a
number of mesodermal tissue types, including osteoblasts, adipocytes, chondrocytes and …

Background Acute lung injury (ALI) together with acute respiratory distress syndrome
(ARDS) are associated with high rate of mortality and morbidity in patients. In the current …