Designing decellularized extracellular matrix‐based bioinks for 3D bioprinting

A Abaci, M Guvendiren - Advanced healthcare materials, 2020 - Wiley Online Library
Abstract 3D bioprinting is an emerging technology to fabricate tissues and organs by
precisely positioning cells into 3D structures using printable cell‐laden formulations known …

The ECM: to scaffold, or not to scaffold, that is the question

JC Valdoz, BC Johnson, DJ Jacobs, NA Franks… - International Journal of …, 2021 - mdpi.com
The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell
survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the …

Applications of decellularized extracellular matrix in bone and cartilage tissue engineering

YS Kim, M Majid, AJ Melchiorri… - … & translational medicine, 2019 - Wiley Online Library
Regenerative therapies for bone and cartilage injuries are currently unable to replicate the
complex microenvironment of native tissue. There are many tissue engineering approaches …

[HTML][HTML] Tissue engineering by decellularization and 3D bioprinting

E Garreta, R Oria, C Tarantino, M Pla-Roca, P Prado… - Materials Today, 2017 - Elsevier
Discarded human donor organs have been shown to provide decellularized extracellular
matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion

KM Stearns‐Reider, A D'Amore, K Beezhold… - Aging cell, 2017 - Wiley Online Library
Age‐related declines in skeletal muscle regeneration have been attributed to muscle stem
cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis …

Strategies to engineer tendon/ligament-to-bone interface: biomaterials, cells and growth factors

SF Tellado, ER Balmayor, M Van Griensven - Advanced drug delivery …, 2015 - Elsevier
Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

ECM in differentiation: a review of matrix structure, composition and mechanical properties

A Padhi, AS Nain - Annals of biomedical engineering, 2020 - Springer
Stem cell regenerative potential owing to the capacity to self-renew as well as differentiate
into other cell types is a promising avenue in regenerative medicine. Stem cell niche not …

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

S Wu, Y Wang, PN Streubel, B Duan - Acta biomaterialia, 2017 - Elsevier
Non-woven nanofibrous scaffolds have been developed for tendon graft application by
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …

Multilayered polycaprolactone/gelatin fiber-hydrogel composite for tendon tissue engineering

G Yang, H Lin, BB Rothrauff, S Yu, RS Tuan - Acta biomaterialia, 2016 - Elsevier
Regeneration of injured tendon and ligament (T&L) remains a clinical challenge due to their
poor intrinsic healing capacity. Tissue engineering provides a promising alternative …