Extensive review on breast cancer its etiology, progression, prognostic markers, and treatment

H Swaminathan, K Saravanamurali, SA Yadav - Medical Oncology, 2023 - Springer
As the most frequent and vulnerable malignancy among women, breast cancer universally
manifests a formidable healthcare challenge. From a biological and molecular perspective, it …

[HTML][HTML] Nanomaterial-assisted CRISPR gene-engineering–A hallmark for triple-negative breast cancer therapeutics advancement

J Farheen, NS Hosmane, R Zhao, Q Zhao, MZ Iqbal… - Materials Today Bio, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is the most violent class of tumor and accounts for 20–
24% of total breast carcinoma, in which frequently rare mutation occurs in high frequency …

RNA-based classification of homologous recombination deficiency in racially diverse patients with breast cancer

A Walens, SC Van Alsten, LT Olsson, MA Smith… - … Biomarkers & Prevention, 2022 - AACR
Background: Aberrant expression of DNA repair pathways such as homologous
recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered …

[HTML][HTML] SARS-CoV-2 and coronavirus disease mitigation: treatment options, vaccinations and variants

A Khamees, J Bani-Issa, MSA Zoubi, T Qasem… - Pathogens, 2022 - mdpi.com
COVID-19 is caused by a novel coronavirus (2019-nCoV), which was declared as a
pandemic after it emerged in China 2019. A vast international effort has been conducted to …

Landmark series: the cancer genome atlas and the study of breast cancer disparities

JA Johnson, BJ Moore, G Syrnioti, CM Eden… - Annals of Surgical …, 2023 - Springer
Race-related variation in breast cancer incidence and mortality are well-documented in the
United States. The effect of genetic ancestry on disparities in tumor genomics, risk factors …

[HTML][HTML] Moderate exercise modulates tumor metabolism of triple-negative breast cancer

A Vulczak, AO Souza, GD Ferrari, AECS Azzolini… - Cells, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) stands out for its aggressiveness and accelerated rate
of proliferation. Evidence shows that exercise may exert antitumorigenic effects, but the …

Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas

LA Williams, KA Hoadley, HB Nichols, J Geradts… - Cancer Causes & …, 2019 - Springer
Background The dominant invasive breast cancer histologic subtype, ductal carcinoma,
shows intrinsic subtype diversity. However, lobular breast cancers are predominantly …

Decoding the link between WWOX and p53 in aggressive breast cancer

SK Abdeen, RI Aqeilan - Cell Cycle, 2019 - Taylor & Francis
Basal-like breast cancer (BLBC) and triple-negative breast cancer (TNBC) are aggressive
forms of human breast cancer with poor prognosis and limited treatment response …

[HTML][HTML] Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications

EH Allott, Y Shan, M Chen, X Sun… - Breast cancer research …, 2020 - Springer
Purpose Female breast cancer demonstrates bimodal age frequency distribution patterns at
diagnosis, interpretable as two main etiologic subtypes or groupings of tumors with shared …

Survival differences by race/ethnicity among children and adolescents diagnosed with germ cell tumors

LA Williams, AL Frazier… - International journal of …, 2020 - Wiley Online Library
Survival differences by racial and ethnic group have been reported in children and
adolescents with germ cell tumors (GCTs), but whether these differences depend on stage of …