Protein glycosylation and tumor microenvironment alterations driving cancer hallmarks
Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …
Glycosylation and integrin regulation in cancer
Integrins are transmembrane receptors that coordinate extracellular matrix (ECM)–cell and
cell–cell interactions, signal transmission, gene expression, and cell function. The aberration …
cell–cell interactions, signal transmission, gene expression, and cell function. The aberration …
Recent advances in glycoproteomic analysis by mass spectrometry
S Suttapitugsakul, F Sun, R Wu - Analytical chemistry, 2019 - ACS Publications
Glycosylation is one of the most common protein modifications and is essential for cells. This
modification is exceptionally complex because glycans are highly diverse and can be …
modification is exceptionally complex because glycans are highly diverse and can be …
Clinical therapies and nano drug delivery systems for urinary bladder cancer
Bladder cancer is the 10 th most commonly occurring malignancy worldwide with a 75% of 5-
year survival rate, while it ranks 13 th among the deaths occurring due to cancer. The …
year survival rate, while it ranks 13 th among the deaths occurring due to cancer. The …
The effect of hypoxia and hypoxia-associated pathways in the regulation of antitumor response: friends or foes?
R Abou Khouzam, RF Zaarour… - Frontiers in …, 2022 - frontiersin.org
Hypoxia is an environmental stressor that is instigated by low oxygen availability. It fuels the
progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic …
progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic …
Golgi pH, ion and redox homeostasis: how much do they really matter?
S Kellokumpu - Frontiers in cell and developmental biology, 2019 - frontiersin.org
Exocytic and endocytic compartments each have their own unique luminal ion and pH
environment that is important for their normal functioning. A failure to maintain this …
environment that is important for their normal functioning. A failure to maintain this …
Magnetic nanoparticles: current trends and future aspects in diagnostics and nanomedicine
NVS Vallabani, S Singh… - Current drug metabolism, 2019 - ingentaconnect.com
Background: Biomedical applications of Magnetic Nanoparticles (MNPs) are creating a
major impact on disease diagnosis and nanomedicine or a combined platform called …
major impact on disease diagnosis and nanomedicine or a combined platform called …
Recent advances in lectin-based affinity sorbents for protein glycosylation studies
A Goumenou, N Delaunay, V Pichon - Frontiers in Molecular …, 2021 - frontiersin.org
Glycosylation is one of the most significant post-translational modifications occurring to
proteins, since it affects some of their basic properties, such as their half-life or biological …
proteins, since it affects some of their basic properties, such as their half-life or biological …
Transcriptional state dynamics lead to heterogeneity and adaptive tumor evolution in urothelial bladder carcinoma
A Biswas, S Sahoo, GM Riedlinger… - Communications …, 2023 - nature.com
Intra-tumor heterogeneity contributes to treatment failure and poor survival in urothelial
bladder carcinoma (UBC). Analyzing transcriptome from a UBC cohort, we report that intra …
bladder carcinoma (UBC). Analyzing transcriptome from a UBC cohort, we report that intra …
A systematic review on the implications of O-linked glycan branching and truncating enzymes on cancer progression and metastasis
Glycosylation is the most commonly occurring post-translational modifications, and is
believed to modify over 50% of all proteins. The process of glycan modification is directed by …
believed to modify over 50% of all proteins. The process of glycan modification is directed by …