Sumoylation is an essential post-translational modification that is catalysed by a small
number of modifying enzymes but regulates thousands of target proteins in a dynamic …

Post-translational protein modification by small ubiquitin-like modifier (SUMO), termed
sumoylation, is an important mechanism in cellular responses to stress and one that …

SUMOylation is a reversible post-translational modification which has emerged as a crucial
molecular regulatory mechanism, involved in the regulation of DNA damage repair, immune …

Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

Abstract N 6-Methyladenosine (m6A) is the most abundant modification within diverse RNAs
including mRNAs and lncRNAs and is regulated by a reversible process with important …

Small ubiquitin-like modifier (SUMO) family proteins regulate target-protein functions by post-
translational modification. However, a potent and selective inhibitor targeting the SUMO …

The small ubiquitin-like modifier (SUMO) signaling cascade is critical for gene expression,
genome integrity, and cell cycle progression. In this review, we discuss the important role …

Objective Pancreatic ductal adenocarcinoma (PDAC) has the characteristics of high-density
desmoplastic stroma, a distinctive immunosuppressive microenvironment and is profoundly …

Activated SUMOylation is a hallmark of cancer. Starting from a targeted screening for SUMO-
regulated immune evasion mechanisms, we identified an evolutionarily conserved function …

Post-translational modifications of cellular substrates with ubiquitin and ubiquitin-like
proteins (UBLs), including ubiquitin, SUMOs, and neural precursor cell–expressed …