Bone repair and regeneration require physiological cues, including mechanical, electrical,
and biochemical activity. Many biomaterials have been investigated as bioactive scaffolds …

Cell therapy is a valuable strategy for the replacement of bone grafts and repair bone
defects, and mesenchymal stem cells (MSCs) are the most frequently used cells. This study …

The maintenance and incremental growth of the alveolar bone at the tooth extraction site, to
achieve the required height and width for implant restoration, remains a major clinical …

Periodontal disease is one of the most common oral diseases with the highest incidence
world-wide. In particular, the treatment of periodontal bone defects caused by periodontitis …

The secretome present in the conditioned medium (CM) of mesenchymal stem cells (MSCs)
is a promising tool to be used in therapies to promote bone regeneration. Considering the …

Traditional bioreactor systems involve the use of three-dimensional (3D) scaffolds or stem
cell aggregates, limiting the accessibility to the production of cell-secreted biomolecules …

Aim: This study sets out to investigate the possible effects of miRNA-148a-3p (miR-148a-3p)
on osteoblast differentiation and bone remodeling following osteoporosis. Materials & …

Since their discovery, mesenchymal stromal cells (MSCs) have received a lot of attention,
mainly due to their self-renewal potential and multilineage differentiation capacity. For these …

Introduction The jabuticaba peel extract (JPE) contains bioactive compounds that regulate
fat metabolism. Because the negative correlation between fat accumulation and bone …

Osteoporosis (OP) is a common debilitating metabolic bone disorder manifested by poor
mineral density and deteriorated skeleton. Stem cell therapies are being considered as …