Kappa opioid receptors (KORs) in the central nervous system have been known to be
important regulators of a variety of psychiatry illnesses, including anxiety and addiction, but …

Recent technical developments have transformed how neuroscientists can probe brain
function. What was once thought to be difficult and perhaps impossible, stimulating a single …

Substance and alcohol use disorders impose large health and economic burdens on
individuals, families, communities, and society. Neither prevention nor treatment efforts are …

Chronic alcohol consumption and withdrawal leads to anxiety, escalated alcohol drinking
behavior, and alcohol dependence. Alterations in the function of key structures within the …

Adolescence represents a particularly vulnerable period during which exposure to stressors
can precipitate the onset of psychiatric disorders and addiction. The basolateral amygdala …

Chronic stress contributes to the neuropathology of mental health disorders, including those
associated with anxiety. The basolateral amygdala (BLA) coordinates emotional behavioral …

Alcoholism is associated with changes in brain reward and control systems, including the
prefrontal cortex. In prefrontal areas, the orbitofrontal cortex (OFC) has been suggested to …

Alcohol-use-disorders are chronic relapsing illnesses, often co-morbid with anxiety. We
have previously shown using the “drinking-in-the-dark” model in mice that the stimulation of …

Alcohol use disorder (AUD) is frequently comorbid with mood disorders, and these co-
occurring neuropsychiatric disorders contribute to the development and maintenance of …

Abstract Alcohol Use Disorder (AUD) is a leading cause of death and disability worldwide,
but current treatments are insufficient in fully addressing the symptoms that often lead to …